Top 200 Drugs (Updated for 2026)
Check to see which drugs made the top 200 drug list. (plus 40 extra drugs that go on and off the top 200)
The drug list can be easily sorted by order of most prescribed, brand or generic name, drug class, alphabetical order, and DEA schedule. Click on the titles of the columns to change the order in which the drugs are shown. Click the title again to rearrange the drugs in another way.
| Drug # | Generic Name | Brand Name | Drug Class | DEA Schedule |
|---|---|---|---|---|
| 1 | zolpidem | Ambien | Sleep Aid | C-IV |
| 2 | amoxicillin | Amoxil | Antibiotic | - |
| 3 | amoxicillin + clavulanate | Augmentin | Antibiotic | - |
| 4 | metformin | Glucophage | Antidiabetic | - |
| 5 | furosemide | Lasix | Diuretic/antihypertensive | - |
| 6 | atorvastatin | Lipitor | Cholesterol lowering | - |
| 7 | metoprolol tartrate | Lopressor | Antihypertensive | - |
| 8 | hydrochlorothiazide (HCTZ) | Microzide | Diuretic/antihypertensive | - |
| 9 | esomeprazole | Nexium | Antacid (PPI) | - |
| 10 | amlodipine | Norvasc | Antihypertensive | - |
| 11 | oxycodone + APAP | Percocet | Analgesic | C-II |
| 12 | omeprazole | Prilosec | Antacid (PPI) | - |
| 13 | lisinopril | Prinivil / Zestril | Antihypertensive | - |
| 14 | levothyroxine | Synthroid | Thyroid hormone replacement | - |
| 15 | atenolol | Tenormin | Antihypertensive | - |
| 16 | hydrocodone + APAP | Vicodin | Analgesic | C-II |
| 17 | alprazolam | Xanax | Antianxiety | C-IV |
| 18 | azithromycin | Zithromax | Antibiotic | - |
| 19 | simvastatin | Zocor | Cholesterol lowering | - |
| 20 | sertraline | Zoloft | Antidepressant (SSRI) | - |
| 21 | ibuprofen | Advil | Analgesic (NSAID) | - |
| 22 | lorazepam | Ativan | Antianxiety | C-IV |
| 23 | citalopram | Celexa | Antidepressant (SSRI) | - |
| 24 | ciprofloxacin | Cipro | Antibiotic | - |
| 25 | warfarin | Coumadin | Anticoagulant | - |
| 26 | chlorthalidone | Thalitone | Diuretic/antihypertensive | - |
| 27 | cyclobenzaprine | Flexeril | Muscle relaxer | - |
| 28 | fluticasone | Flonase | Anti-inflammatory steroid | - |
| 29 | cephalexin | Keflex | Antibiotic | - |
| 30 | clonazepam | Klonopin | Antianxiety | C-IV |
| 31 | escitalopram | Lexapro | Antidepressant (SSRI) | - |
| 32 | gabapentin | Neurontin | Anticonvulsant | - |
| 33 | clopidogrel | Plavix | Antiplatelet | - |
| 34 | pravastatin | Pravachol | Cholesterol lowering | - |
| 35 | albuterol | ProAir / Ventolin / Proventil | Bronchodilator | - |
| 36 | fluoxetine | Prozac | Antidepressant (SSRI) | - |
| 37 | sulfamethoxazole + trimethoprim | Septra | Antibiotic combination | - |
| 38 | montelukast | Singulair | Anti-asthmatic | - |
| 39 | prednisone | Deltasone | Anti-inflammatory steroid | - |
| 40 | tramadol | Ultram | Analgesic (narcotic-like) | C-IV |
| 41 | fluticasone + salmeterol | Advair | Steroid + bronchodilator | - |
| 42 | naproxen | Aleve | Analgesic (NSAID) | - |
| 43 | cetirizine | Zyrtec | Antihistamine (H1) | - |
| 44 | carvedilol | Coreg | Antihypertensive | - |
| 45 | rosuvastatin | Crestor | Cholesterol lowering | - |
| 46 | duloxetine | Cymbalta | Antidepressant | - |
| 47 | trazodone | Desyrel | Antidepressant | - |
| 48 | fluconazole | Diflucan | Antifungal | - |
| 49 | valsartan | Diovan | Antihypertensive | - |
| 50 | venlafaxine | Effexor | Antidepressant | - |
| 51 | amitriptyline | Elavil | Antidepressant | - |
| 52 | alendronate | Fosamax | Bone strengthener | - |
| 53 | potassium chloride | Klor-Con | Electrolyte | - |
| 54 | lovastatin | Mevacor | Cholesterol lowering | - |
| 55 | meloxicam | Mobic | Analgesic (NSAID.) | - |
| 56 | paroxetine | Paxil | Antidepressant (SSRI) | - |
| 57 | diazepam | Valium | Antianxiety | C-IV |
| 58 | doxycycline | Vibramycin | Antibiotic | - |
| 59 | prazosin | Minipress | Antihypertensive | - |
| 60 | nebivolol | Bystolic | Antihypertensive | - |
| 61 | pioglitazone | Actos | Antidiabetic | - |
| 62 | clonidine | Catapres | Antihypertensive/sleep aid | - |
| 63 | celecoxib | Celebrex | Analgesic (NSAID) | - |
| 64 | tamsulosin | Flomax | Reduces enlarged prostate | - |
| 65 | insulin glargine | Lantus | Insulin | - |
| 66 | levofloxacin | Levaquin | Antibiotic | - |
| 67 | methylprednisolone | Medrol | Anti-inflammatory steroid | - |
| 68 | oxycodone | Oxycontin | Analgesic | C-II |
| 69 | promethazine | Phenergan | Antiemetic | - |
| 70 | lansoprazole | Prevacid | Antacid (PPI) | - |
| 71 | sacubitril + valsartan | Entresto | Heart failure (ARNI) | - |
| 72 | quetiapine | Seroquel | Antipsychotic | - |
| 73 | rimegepant | Nurtec ODT | Antimigraine (CGRP antagonist) | - |
| 74 | fenofibrate | Tricor | Cholesterol lowering | - |
| 75 | codeine + apap | Tylenol 3 | Analgesic | C-III |
| 76 | enalapril | Vasotec | Antihypertensive | - |
| 77 | sildenafil | Viagra | Erectile dysfunction | - |
| 78 | dexmethylphenidate | Focalin | ADHD | C-II |
| 79 | ethinyl estradiol + drospirenone | Yaz | Birth control | - |
| 80 | allopurinol | Zyloprim | Antigout | - |
| 81 | spironolactone | Aldactone | Diuretic/antihypertensive | - |
| 82 | ramipril | Altace | Antihypertensive | - |
| 83 | glimepiride | Amaryl | Antidiabetic | - |
| 84 | methylphenidate | Concerta | ADHD | C-II |
| 85 | losartan | Cozaar | Antihypertensive | - |
| 86 | levocetirizine | Xyzal | Antihistamine | - |
| 87 | folic acid | Folvite | Vitamin supplement | - |
| 88 | isosorbide mononitrate | Imdur | Anti-angina (chest pain) | - |
| 89 | digoxin | Lanoxin | Treats heart failure/arrhythmia | - |
| 90 | pregabalin | Lyrica | Anticonvulsant/Antinerve pain | C-V |
| 91 | triamcinolone | Nasacort | Anti-inflammatory steroid | - |
| 92 | desvenlafaxine | Pristiq | Antidepressant | - |
| 93 | cefdinir | Omnicef | Antibiotic | - |
| 94 | aspirin | Ecotrin | Antiplatelet / analgesic | - |
| 95 | rivaroxaban | Xarelto | Anticoagulant | - |
| 96 | temazepam | Restoril | Sleep aid | C-IV |
| 97 | oseltamivir | Tamiflu | Antiviral (Flu) | - |
| 98 | valacyclovir | Valtrex | Antiviral | - |
| 99 | labetalol | Trandate | Antihypertensive | - |
| 100 | ezetimibe | Zetia | Cholesterol lowering | - |
| 101 | aripiprazole | Abilify | Antipsychotic | - |
| 102 | amphetamine + dextroamphetamine | Adderall | ADHD | C-II |
| 103 | phentermine | Adipex | Appetite suppressant | C-IV |
| 104 | donepezil | Aricept | Anti-Alzheimer's | - |
| 105 | lisinopril + HCTZ | Zestoretic | Antihypertensive + diuretic | - |
| 106 | diclofenac | Cataflam | Analgesic (NSAID) | - |
| 107 | olmesartan | Benicar | Antihypertensive (ARB) | - |
| 108 | clindamycin | Cleocin | Antimicrobial | - |
| 109 | metronidazole | Flagyl | Antimicrobial | - |
| 110 | glipizide | Glucotrol | Antidiabetic | - |
| 111 | lamotrigine | Lamictal | Anticonvulsant | - |
| 112 | cyanocobalamin | Nascobal | Vitamin B12 supplement | - |
| 113 | evolocumab | Repatha | Cholesterol lowering (PCSK9 inhibitor) | - |
| 114 | benazepril | Lotensin | Antihypertensive | - |
| 115 | ethinyl estradiol + norgestimate | Ortho Tri Cyclen | Birth Control | - |
| 116 | metoclopramide | Reglan | GI motility stimulant | - |
| 117 | risperidone | Risperdal | Antipsychotic | - |
| 118 | tiotropium | Spiriva | Reduces mucus secretion/bronchodilator | - |
| 119 | verapamil | Verelan | Anti-arrhythmia | - |
| 120 | hydroxyzine | Vistaril | Antihistamine | - |
| 121 | meclizine | Antivert | Antivertigo | - |
| 122 | buspirone | BuSpar | Antianxiety | - |
| 123 | diltiazem | Cardizem | Antihypertensive | - |
| 124 | doxazosin | Cardura | Reduces enlarged prostate | - |
| 125 | divalproex | Depakote | Anticonvulsant | - |
| 126 | linaclotide | Linzess | IBS with constipation | - |
| 127 | nitrofurantoin | Furadantin | Antibiotic | - |
| 128 | losartan + HCTZ | Hyzaar | Antihypertensive + diuretic | - |
| 129 | propranolol | Inderal | Antihypertensive | - |
| 130 | sitagliptin | Januvia | Antidiabetic | - |
| 131 | pramipexole | Mirapex | Anti-tremor (Parkinson's disease) | - |
| 132 | apixaban | Eliquis | Anticoagulant | - |
| 133 | mirtazapine | Remeron | Antidepressant | - |
| 134 | azelastine | Astelin | Antihistamine (nasal) | - |
| 135 | buprenorphine + naloxone | Suboxone | Opioid Recovery | C-III |
| 136 | topiramate | Topamax | Anticonvulsant | - |
| 137 | lisdexamfetamine | Vyvanse | ADHD | C-II |
| 138 | bupropion | Wellbutrin | Antidepressant | - |
| 139 | latanoprost | Xalatan | Antiglaucoma | - |
| 140 | acyclovir | Zovirax | Antiviral | - |
| 141 | amlodipine + benazepril | Lotrel | Antihypertensive (CCB + ACE) | - |
| 142 | mesalamine | Lialda | Anti-inflammatory (ulcerative colitis) | - |
| 143 | irbesartan | Avapro | Antihypertensive | - |
| 144 | mupirocin | Bactroban | Topical antibacterial | - |
| 145 | estradiol | Estrace | Estrogen hormone replacement | - |
| 146 | albuterol + ipratropium | Combivent | Bronchodilator/anti-mucus | - |
| 147 | morphine sulfate ER | MS Contin | Analgesic | C-II |
| 148 | mirabegron | Myrbetriq | Overactive bladder | - |
| 149 | butalbital/apap/caffeine | Fioricet | Antimigraine | - |
| 150 | polyethylene glycol | MiraLAX | Laxative | - |
| 151 | terazosin | Hytrin | Antihypertensive | - |
| 152 | sumatriptan | Imitrex | Antimigraine | - |
| 153 | guanfacine | Tenex | Antihypertensive and attention deficit hyperactivity disorder (ADHD) | - |
| 154 | carbamazepine | Tegretol | Anticonvulsant | - |
| 155 | methimazole | Tapazole | Antithyroid | - |
| 156 | famotidine | Pepcid | Antacid | - |
| 157 | nifedipine | Procardia | Antihypertensive | - |
| 158 | finasteride | Proscar | Reduces enlarged prostate | - |
| 159 | methotrexate | Trexall | Antirheumatic | - |
| 160 | benzonatate | Tessalon Perles | Cough suppressant | - |
| 161 | ergocalciferol | Drisdol | Vitamin D supplement | - |
| 162 | torsemide | Demadex | Diuretic (loop) | - |
| 163 | dicyclomine | Bentyl | Antispasmodic (intestines) | - |
| 164 | nirmatrelvir + ritonavir | Paxlovid | Antiviral (COVID-19) | - |
| 165 | varenicline | Chantix | Smoking cessation | - |
| 166 | anastrozole | Arimidex | Breast cancer (aromatase inhibitor) | - |
| 167 | insulin lispro | Humalog | Insulin (short acting) | - |
| 168 | insulin degludec | Tresiba | Insulin (long acting) | - |
| 169 | memantine | Namenda | Anti-Alzheimer's | - |
| 170 | nitroglycerin | Nitrostat | Anti-angina | - |
| 171 | insulin aspart | NovoLog | Insulin | - |
| 172 | dulaglutide | Trulicity | Antidiabetic (Increases insulin secretion from pancreas) | - |
| 173 | nabumetone | Relafen | Analgesic (NSAID) | - |
| 174 | ropinirole | Requip | Anti-Parkinson's | - |
| 175 | methocarbamol | Robaxin | Muscle relaxer | - |
| 176 | clobetasol | Temovate | Anti-inflammatory steroid | - |
| 177 | tizanidine | Zanaflex | Muscle relaxer | - |
| 178 | bisoprolol | Zebeta | Antihypertensive | - |
| 179 | ondansetron | Zofran | Antiemetic | - |
| 180 | olanzapine | Zyprexa | Antipsychotic | - |
| 181 | hydralazine | Apresoline | Antihypertensive | - |
| 182 | moxifloxacin | Avelox | Antibiotic | - |
| 183 | testosterone | AndroGel | Androgen hormone | C-III |
| 184 | triamterene + HCTZ | Dyazide | Antihypertensive (2 diuretics) | - |
| 185 | lithium | Lithobid | Mood stabilizer (bipolar) | - |
| 186 | adalimumab | Humira | Immunosuppressive (arthritis, Crohn's disease, and ulcerative colitis) | - |
| 187 | phenytoin | Dilantin | Anticonvulsant | - |
| 188 | oxybutynin | Ditropan | Overactive bladder | - |
| 189 | levetiracetam | Keppra | Anticonvulsant | - |
| 190 | liraglutide | Victoza | Antidiabetic (Increases insulin secretion from pancreas) | - |
| 191 | baclofen | Lioresal | Muscle relaxer | - |
| 192 | oxcarbazepine | Trileptal | Anticonvulsant | - |
| 193 | ketoconazole | Nizoral | Antifungal | - |
| 194 | nortriptyline | Pamelor | Antidepressant | - |
| 195 | hydroxychloroquine | Plaquenil | Arthritis/lupus | - |
| 196 | pantoprazole | Protonix | Antacid (PPI) | - |
| 197 | phenazopyridine | Pyridium | Analgesic (urinary) | - |
| 198 | atomoxetine | Strattera | ADHD (nonscheduled) | - |
| 199 | metformin + sitagliptin | Janumet | Antidiabetic combination | - |
| 200 | empagliflozin | Jardiance | Antidiabetic | - |
| 201 | ticagrelor | Brilinta | Antiplatelet | - |
| 202 | tadalafil | Cialis | Erectile dysfunction | - |
| 203 | colchicine | Colcrys | Antigout | - |
| 204 | fluticasone + umeclidinium + vilanterol | Trelegy Ellipta | COPD/asthma (steroid + 2 bronchodilators) | - |
| 205 | dexlansoprazole | Dexilant | Antacid (PPI) | - |
| 206 | brimonidine | Alphagan P | Antiglaucoma | - |
| 207 | ferrous sulfate | Feosol | Iron supplement | - |
| 208 | thyroid | Armour Thyroid | Thyroid hormone replacement | - |
| 209 | lurasidone | Latuda | Antipsychotic | - |
| 210 | liothyronine | Cytomel | Thyroid hormone replacement | - |
| 211 | tretinoin | Retin-A | Acne (topical retinoid) | - |
| 212 | dupilumab | Dupixent | Immunomodulator (eczema, asthma) | - |
| 213 | tirzepatide | Mounjaro | Antidiabetic (GIP/GLP-1 agonist) | - |
| 214 | olopatadine | Patanase/Patanol | Antihistamine | - |
| 215 | ethinyl estradiol + norethindrone | Loestrin | Birth control | - |
| 216 | dapagliflozin | Farxiga | Antidiabetic (SGLT2 inhibitor) | - |
| 217 | prednisolone | Orapred | Anti-inflammatory steroid | - |
| 218 | budesonide | Uceris | Anti-inflammatory | - |
| 219 | budesonide + formoterol | Symbicort | Steroid + bronchodilator | - |
| 220 | solifenacin | Vesicare | Bladder relaxant | - |
| 221 | fluticasone + vilanterol | Breo Ellipta | Steroid + bronchodilator | - |
| 222 | progesterone | Prometrium | Progestin hormone | - |
| 223 | amiodarone | Cordarone | Antiarrhythmic | - |
| 224 | norethindrone | Aygestin | Progestin hormone | - |
| 225 | etanercept | Enbrel | Immunosuppressant | - |
| 226 | emtricitabine + tenofovir | Truvada | Antiviral (HIV treatment/PrEP) | - |
| 227 | lidocaine patch | Lidoderm | Local anesthetic | - |
| 228 | omega-3-acid ethyl esters | Lovaza | Triglyceride lowering | - |
| 229 | enoxaparin | Lovenox | Anticoagulant | - |
| 230 | rizatriptan | Maxalt | Antimigraine | - |
| 231 | telmisartan | Micardis | Antihypertensive (ARB) | - |
| 232 | semaglutide | Ozempic | Antidiabetic (GLP-1 agonist) | - |
| 233 | chlorhexidine gluconate | Peridex | Antiseptic | - |
| 234 | ethinyl estradiol + etonogestrel | NuvaRing | Birth control (vaginal ring) | - |
| 235 | tacrolimus | Prograf | Immunosuppressant (transplant) | - |
| 236 | metoprolol succinate | Toprol-XL | Antihypertensive (BB) | - |
| 237 | travoprost | Travatan | Antiglaucoma | - |
| 238 | cyclosporine | Restasis | Dry eye (ophthalmic) | - |
| 239 | alfuzosin | Uroxatral | Benign prostatic hyperplasia-BPH, increases urinary flow | - |
| 240 | zoster vaccine | Shingrix | Shingles vaccine | - |
